The wet mixing granulator is a solid preparation pharmaceutical equipment that has been rapidly developed in recent years. In the process, the two-step mixing and granulation process are combined, which saves time and meets GMP requirements and reduces cross-contamination. Increased efficiency is a quick and easy way to save users. It is reported that the efficient wet mixing granulator improves production efficiency, saves labor costs, and makes tablet production more scientific and more stable.
Efficient wet granulator is suitable for the mixing of powder and powder in the pharmaceutical, chemical, food and other industries. It is widely used in most pharmaceutical companies today.
High-efficiency wet granulator products have the following characteristics: due to the effect of centrifugal force, the bottom feed material leaves the bottom material continuously and upwardly along the wall of the drum, and the upper material falls down from the center to make the material circulate to form a vortex; The bulk material sent by the feed leaf pulp is completely broken; due to the high-speed rotation of the above two kinds of leaf pulp, the material can be uniformly mixed in a relatively short period of time. The mixing speed and the uniform speed are various domestic blends. Unmatched by the machine, the mixed material has no granules and the mixing speed is 100%.
According to industry insiders, efficient wet granulators can increase production efficiency and are ideal for capsule production. Such as Zhangjiagang City Chuangcheng Machinery Manufacturing Co., Ltd. R & D and production of high efficiency wet granulator machine by the programmable control (human machine interface - options), unified process, to ensure stable quality, but also for manual operation, easy to explore the process Parameters and processes. The unit integrates mixing, wet granulation, whole grain and drying, which saves manpower resources and improves production efficiency. It is the ideal equipment for the production of proprietary Chinese medicine granules, tablets and capsules.
According to the analysis of the relevant technical personnel, the highly efficient wet mixing granulator adopts the technology of inverted cone-shaped granulation and the special stirrer and cutter of the switch in the structure, so that the material is rolled uniformly and the granulated product is more uniform and reliable. The bottom of the tank is a sandwich layer with a built-in water-cooled circulation system. The constant temperature performance is better than that of a general air-cooled system, which improves the quality of the pellets. Both stirring paddles and cutting knives are frequency-controlled, which makes it easy to control the particle size to meet the diversity of pharmaceutical processes. The use of compressed air to seal the drive shaft eliminates dust adhesion; it can be switched to purified water during cleaning and can be cleaned automatically; with a blade lift system, it is beneficial to paddle and pot cleaning. The lid is automatically lifted, and the discharge port is matched with the drying equipment. The large model comes with an escalator and is easy to operate. The discharge port is arc-shaped to prevent dead angles.
In principle, the granulation is fluidized, the granulation is approximately spherical, and the fluidity is good. Compared with the traditional process, the amount of adhesive is reduced by up to 25%, so the drying time can be shortened. In the control, programmable control can be used to automatically run, or manual control, easy to explore process parameters and processes; easy to operate, adjust the time controller according to the process arrangement, each dry mixing 2min, granulation 1 ~ 4min, a The cycle can complete the mixing granulation process, and the efficiency is 4 to 5 times higher than the traditional process. In terms of safety: The entire operation has strict safety protection measures. It operates in a closed container and is equipped with a safety interlock device. When the container lid is opened, the power is automatically cut off.
The preparation plays a role in the industrial chain of the pharmaceutical industry. It not only supports the development of new drugs, but also helps the new drugs to achieve the final industrialization. Granulation is an important part of the production process of solid pharmaceuticals. Choosing a reasonable granulator is of great significance for the development of the company. The efficient wet granulator fully guarantees a more uniform and reliable granulation product. With the development of the formulation pharmaceutical industry, the highly efficient wet granulator will play a major role. However, from the current point of view, China's high-efficiency wet granulation machine still has certain deficiencies, so related companies still need to continue to make efforts to strengthen the innovative research and development of equipment, to produce more perfect products, in order to promote the steady development of the formulation pharmaceutical industry.
Efficient wet granulator is suitable for the mixing of powder and powder in the pharmaceutical, chemical, food and other industries. It is widely used in most pharmaceutical companies today.
High-efficiency wet granulator products have the following characteristics: due to the effect of centrifugal force, the bottom feed material leaves the bottom material continuously and upwardly along the wall of the drum, and the upper material falls down from the center to make the material circulate to form a vortex; The bulk material sent by the feed leaf pulp is completely broken; due to the high-speed rotation of the above two kinds of leaf pulp, the material can be uniformly mixed in a relatively short period of time. The mixing speed and the uniform speed are various domestic blends. Unmatched by the machine, the mixed material has no granules and the mixing speed is 100%.
According to industry insiders, efficient wet granulators can increase production efficiency and are ideal for capsule production. Such as Zhangjiagang City Chuangcheng Machinery Manufacturing Co., Ltd. R & D and production of high efficiency wet granulator machine by the programmable control (human machine interface - options), unified process, to ensure stable quality, but also for manual operation, easy to explore the process Parameters and processes. The unit integrates mixing, wet granulation, whole grain and drying, which saves manpower resources and improves production efficiency. It is the ideal equipment for the production of proprietary Chinese medicine granules, tablets and capsules.
According to the analysis of the relevant technical personnel, the highly efficient wet mixing granulator adopts the technology of inverted cone-shaped granulation and the special stirrer and cutter of the switch in the structure, so that the material is rolled uniformly and the granulated product is more uniform and reliable. The bottom of the tank is a sandwich layer with a built-in water-cooled circulation system. The constant temperature performance is better than that of a general air-cooled system, which improves the quality of the pellets. Both stirring paddles and cutting knives are frequency-controlled, which makes it easy to control the particle size to meet the diversity of pharmaceutical processes. The use of compressed air to seal the drive shaft eliminates dust adhesion; it can be switched to purified water during cleaning and can be cleaned automatically; with a blade lift system, it is beneficial to paddle and pot cleaning. The lid is automatically lifted, and the discharge port is matched with the drying equipment. The large model comes with an escalator and is easy to operate. The discharge port is arc-shaped to prevent dead angles.
In principle, the granulation is fluidized, the granulation is approximately spherical, and the fluidity is good. Compared with the traditional process, the amount of adhesive is reduced by up to 25%, so the drying time can be shortened. In the control, programmable control can be used to automatically run, or manual control, easy to explore process parameters and processes; easy to operate, adjust the time controller according to the process arrangement, each dry mixing 2min, granulation 1 ~ 4min, a The cycle can complete the mixing granulation process, and the efficiency is 4 to 5 times higher than the traditional process. In terms of safety: The entire operation has strict safety protection measures. It operates in a closed container and is equipped with a safety interlock device. When the container lid is opened, the power is automatically cut off.
The preparation plays a role in the industrial chain of the pharmaceutical industry. It not only supports the development of new drugs, but also helps the new drugs to achieve the final industrialization. Granulation is an important part of the production process of solid pharmaceuticals. Choosing a reasonable granulator is of great significance for the development of the company. The efficient wet granulator fully guarantees a more uniform and reliable granulation product. With the development of the formulation pharmaceutical industry, the highly efficient wet granulator will play a major role. However, from the current point of view, China's high-efficiency wet granulation machine still has certain deficiencies, so related companies still need to continue to make efforts to strengthen the innovative research and development of equipment, to produce more perfect products, in order to promote the steady development of the formulation pharmaceutical industry.
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