A U.S. research team reported that they created the world's first nano-valve. The valve controls the entry and exit of molecules, which scientists envisioned in the future to deliver individual drug molecules to cells. University of California, Los Angeles professor Jeffrey Chingk et al developed this nano-valve, composed of two parts. One is an artificially engineered rotamase molecule that is the active "valve" of the valve and the other is a 500 nanometer square porous silicon material that is a fixed part of the valve with a small hole size of only a few nanometers. The UCLA researchers designed this kind of on-off rotaxane that includes a dumbbell-shaped long chain and a molecular ring that moves back and forth linearly between the dumbbells, and the electric force between the molecules drives the molecule ring. Earlier, scientists have verified that this rotaxane can be used as a microelectronic switch.
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