A study published in the journal Dermatology Research found that skin cells have olfactory receptors, and when these receptors are exposed to sandalwood, changes in cell activity can promote wound healing. This study was presided over by Dr. Hans Hart of Germany.
Although it is generally believed that olfactory receptors should respond to odors, this is not always the case. There are about 350 olfactory receptors in the human nose, but previous studies have shown that olfactory receptors are also present in the prostate, and in the intestine. For the first time, the olfactory receptor was found on the outermost layer of the skin formed by keratinocytes. Hart’s team found that when these receptors, called OR2AT4, were close to Sandalwood, they were successfully activated, prompting cell proliferation and cell migration.
Hart said that his team's findings were difficult to persuade the scientific community. "I think this is a mission to persuade my colleagues, especially clinicians, that this huge family of olfactory receptors plays an important role in cell physiology," Hart said.
Hart is curious that this discovery may lead to other applications, such as cancer, because certain cancer T cells have olfactory receptors, as well as applications in cosmetics or wound healing. Sandalwood is ubiquitous in perfumes and incense. "The study of the function of these receptors will be a lot of work, but it may open exciting goals," Hart said.
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